We Are Visionaries
Blending innovation, responsibility, and accessibility to deliver transformative therapeutic solutions.
Our vision at EQUULUS Therapeutics is to turn the promise of psychedelics into real-world therapeutics that transform patients' lives and set a new standard in neuroscience healthcare.




1
EQL-101
Substance Use Disorder
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EQL-101 is being designed as the ultimate-generation Ibogaine analog for the treatment of SUD’s and PTSD. By decoupling hallucinatory pathways from neuroplasticity mechanisms and mitigating cardiotoxicity, Equulus is advancing EQL-101 through IND enabling studies to achieve first in human dosing by Q4 2026.

2
MDMA Analog
PTSD
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Our MDMA-inspired, discovery stage, small molecule is being designed to preserve pro-extinction and pro-social neuroplasticity benefits for the treatment of PTSD while minimizing stimulant load, hyperthermia risk, and abuse liability. Through structure–activity optimization within our 5-HT releaser platform, we aim to decouple therapeutic signaling from unwanted effects for a cardio-safer, non-hallucinogenic profile. Next Milestone: Candidate Selection.

3
Fenfluramine Analog
Obesity & Seizure Disorders
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Our next-generation fenfluramine-class agent is being designed to retain seizure-modifying and appetite-regulating efficacy while reducing historical cardiovascular liabilities associated with legacy fenfluramine. Through structure–activity optimization within our 5-HT releaser platform, the medicinal chemistry is focused on selective serotonergic modulation and improved developability to support use in seizure disorders such as epilepsy and obesity. Next Milestone: Candidate Selection

At EQUULUS Therapeutics, our vision is to turn the promise of psychedelic-inspired science into safe, evidence-based medicines with clear pathways to regulatory approval and payer adoption, delivered at scale so every patient who needs them can access and afford them.
Bob Discordia
CEO and Co-Founder of Equulus

Dr. Robert Discordia, Co-Founder, President & CEO of Equulus Therapeutics, brings 30+ years of leadership across the pharmaceutical and biotech industries. An expert in end-to-end drug development and CMC, he has advanced programs from preclinical through clinical development and commercialization across multiple modalities and therapeutic areas. He is recognized for building high-performing teams, optimizing global development and supply networks, and translating innovation into safe, effective medicines.

Robert Discordia, PhD
Co-Founder, President &
Chief Executive Officer
Dr. Peter Hendricks, Co-Founder, Director, and Chief Advisor on Clinical Psychology at Equulus Therapeutics, is the Heersink Endowed Professor in the Department of Psychiatry and Behavioral Neurobiology at the University of Alabama at Birmingham. A clinical psychologist with deep expertise in CNS disorders and patient-centered outcomes, he has designed and led numerous clinical trials of psychedelic-assisted therapies. Bridging academic rigor with industry execution, he guides Equulus’ clinical psychology strategy to translate evidence into scalable, clinically meaningful therapeutics.

Peter Hendricks, PhD
Co-Founder & Director
Clinical Psychology
Dr. Bruce Blough, Co-Founder, Director on the Board of Directors, and Chief Advisor on Medicinal Chemistry at Equulus, is a veteran medicinal chemist focused on CNS therapeutics and translational drug design. Creator of Equulus’ Serotonin Releaser Technology—developed at Research Triangle Institute (RTI)—he advances novel, neurotherapeutics from hit discovery through lead optimization and IND-enabling studies. He brings decades of experience in SAR, scaffold engineering, and IP strategy, guiding portfolio chemistry, external collaborations, and CMC interfaces to deliver clinically viable candidates.

Bruce Blough, PhD
Co-Founder & Director
Medicinal Chemistry
Co-Founder and Director on the Board of Equulus, Dr. Murnane is Associate Professor of Pharmacology, Toxicology & Neuroscience and of Psychiatry at LSU Health Shreveport and serves as Director of Basic Science Research for the Louisiana Addiction Research Center. A specialist in neuropharmacology and neurotoxicology, his lab investigates addiction and stimulant-induced brain injury using behavioral pharmacology, receptor systems, neurochemistry, and neuroimaging. At Equulus, he guides preclinical model strategy, safety assessment, and mechanism-based decision thresholds that de-risk assets and accelerate IND-enabling progress.

Kevin Murnane, PhD
Co-Founder & Director Neuropharmacology & Neurotoxicology
Drew Mouton, Co-Founder, Director on the Board of Directors, and Chief Business Officer (CBO) of Equulus Therapeutics, advises on corporate strategy, business development, and capital formation.
A seasoned operator, he has driven partnering, licensing, and alliance management; built portfolio and go-to-market strategies; and structured both dilutive and non-dilutive financings to advance clinical programs. At Equulus, he advises on investor relations and strategic collaborations that accelerate our CNS pipeline and build durable enterprise value.

Drew Mouton
Chief Business Officer


Dr. Richard Shelton
University of Alabama at Birmingham

Dr. Bruce Car
Biohaven Pharmaceuticals, CSO

Dr. John Renger
Principal, Neurtuitive,
Former CSO, Cerevel

Pamela Perry
Former SVP, Cerevel Therapeutics

Dr. Neal Naito
CEO, MVK Pharmaceuticals

Dr. Andrew Riley
Assistant Professor of Pharmaceutical Sciences Medicinal Chemistry & Pharmacognosy at the University of Illinois Chicago

Angela Terhune Hargrove
Co-Founder, CSO at First Coast Research Center
Equulus Investor Presentation
Equulus Therapeutics is advancing breakthrough therapeutics for central nervous system (CNS) disorders using a transdiagnostic strategy rooted in disease-driving physiology—guided by an experienced neuroscience team and developed with strategic partners. Open the deck to explore our science, programs, and milestones.

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